Friday, October 24, 2014

All About Pneumococcal Vaccines and Schedules for Children: Children, Pneumococcal Vaccines and Schedules



Although pneumococcal vaccines are still relatively new in the medical world, these vaccines are already saving the lives of many children, as well as older family members, who could be exposed to and thus, contact pneumococcal diseases.

Globally, parents need to be educated regarding the seriousness of pneumococcal diseases, particularly with respect to their children. They should be aware that disease protection and prevention are now possible with the administration of pneumococcal vaccines. Parents everywhere are encouraged to contact their family physicians or pediatricians in order to set up vaccination schedules for their children.

What are pneumococcal diseases?

Pneumococcal diseases are disease processes caused by the pathogenic bacterium, known as streptococcus pneumoniae, or pneumococcus and are the major cause of pneumonia, as well as other medical conditions including sinusitis, otitis media and meningitis. (1)

While millions of people around the world are familiar with pneumonia and streptococcal infections, there are still those who may not be aware that vaccines can protect their children and older family members from them. Many people may be surprised when they find out that such immunization is now possible.

Why is pneumococcal vaccination so important?

"Pneumococcal disease is the leading vaccine-preventable killer of young children worldwide, according to the World Health Organization (WHO), killing over 800,000 and up to a million children a year. Ninety percent of the deaths occur in developing countries." (2)

In other words, pneumococcal vaccine can protect children from pneumococcal disease, as well as prevent the spread of these diseases around the world if they are immunized.

What is pneumococcal vaccine?

"Pneumococcal vaccine is a vaccine against streptococcus pneumoniae, which can be of two different types, namely pneumococcal polysaccharied vaccine and pneumococcal conjugate vaccine." (3)

Which pneumococcal vaccine is specific for children?

"In the USA, a heptavalent pneumococcal conjugate vaccine (PCV7) e.g. {Prenevar) is recommended since 2000, for all children aged 2-23 months and for at-risk children aged 24-59 months." (4)

What is the appropriate schedule for pneumococcal vaccine, with regard to children?

"The normally 4-doses series is given at 2, 4, 6 & 12-14 months of age. Protection is good against deep pneumococcal infections (especially septicemia and meningitis.)" (5)

Will pneumococcal vaccine protect children from all possible types of pneumococcus infection?

One must suggest that the disease protection that a child receives always depends upon the specific type of vaccine that he or she receives. In other words, pneumococcal vaccine is effective in the prevention of pneumococcal disease.

"However, if a child is exposed to a serotype of pneumococcus that is not contained in the vaccine, he/she is not afforded any protection. This limitation, and the ability of capsular polysaccharide conjugate vaccines to promote the spread of non-covered serotypes, has led to research in vaccines that would provide species-wide protection." (6)

More research is necessary to cover all possible serotypes of pneumococcus.

In the meantime, is there also pneumococcal vaccine that is not effective for some children?

"The standard 23-valent vaccines are ineffective for children under two years old." (7)

Generally, when there is a disease process, it is advisable to vaccinate children, parents and grandparents of children, as well as others, in order to reduce the possibility of the spread of infection and reduce the risk of cross infection.

What vaccine protection is available for adult family members?

"Pneumococcal polysaccharide vaccine (Pneumovax is one brand) gives at least 85 % protection in those under 55 years of age for five years or longer. Immunization is suggested for those at highest risk of infection, including those 65 years or older; generally the vaccine should be a single lifetime does, as there is high risk of side effects if repeated." (8)

What are the current guidelines from the American College of Physicians, with regard to pneumococcal vaccine, for both children and their parents?

"The current guidelines of the American College of Physicians call for administration of the immunization between ages 2 and 65 when indicated, or at age 65. If someone received the immunization before age 60, the guidelines call for a one-time re-vaccination." (9)

Are there other times when re-vaccination is required?

“Re-vaccination at periodic intervals is as indicated for those with other conditions such as asplenia or nephrotic syndrome." (10)

What global measures are there to reduce the spread of pneumococcal disease?

"It was announced in February 2006, that the UK government would introduce vaccination with the congugate vaccine in children aged 2, 4 and 13 months. This is (sic-was) expected to start on September 4, 2006 and is (sic-was) to include changes to the immunization program in general. In 2009, the European Medicines Agency approved the use of a 10-valent pneumococcal conjugate vaccine for use in Europe." (11)

What other preventative measures are under way, elsewhere around the world?

"Pneumococcal vaccines Accelerated Development and Introduction Plan (Pneumo ADIP) is a program to accelerate the evaluation and access to new pneumococcal vaccines in the developing world. Pneumo ADIP is funded by the Global Alliance for Vaccines and Immunization (GAVI). Thirty GAVI countries have expressed interest in participating, by 2010. Pneumo ADIP Aims to save 5.4 million children by 2030." (12)

Those who have further questions about pneumococcal vaccine should contact their family physicians or pediatricians. There is also more information available on the Internet or through local public health agencies.



3. Ibid.

4. Ibid.

5. Ibid.

6. Ibid.

7. Ibid.

8. Ibid.

9. Ibid.

10. Ibid.

11. Ibid.

12. Ibid.


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